Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50107423'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50107423 (CHEMBL3600420) Show SMILES CCC[C@@H](NC(=O)c1cscn1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 |r| Show InChI InChI=1S/C19H20ClN5OS/c1-3-4-16(25-19(26)17-10-27-11-23-17)13-7-15(20)18(22-8-13)24-14-6-5-12(2)21-9-14/h5-11,16H,3-4H2,1-2H3,(H,22,24)(H,25,26)/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...				Bioorg Med Chem Lett 25: 3135-41 (2015) Article DOI: 10.1016/j.bmcl.2015.06.008 BindingDB Entry DOI: 10.7270/Q2DZ0B3G
					More data for this Ligand-Target Pair