Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50149793'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50149793 (3-(2-Methyl-thiazol-4-ylethynyl)-5-phenyl-pyridine...) Show SMILES Cc1nc(cs1)C#Cc1cncc(c1)-c1ccccc1 Show InChI InChI=1S/C17H12N2S/c1-13-19-17(12-20-13)8-7-14-9-16(11-18-10-14)15-5-3-2-4-6-15/h2-6,9-12H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement by compound of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortical membranes				Bioorg Med Chem Lett 14: 3993-6 (2004) Article DOI: 10.1016/j.bmcl.2004.05.037 BindingDB Entry DOI: 10.7270/Q2T43SKQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50149793 (3-(2-Methyl-thiazol-4-ylethynyl)-5-phenyl-pyridine...) Show SMILES Cc1nc(cs1)C#Cc1cncc(c1)-c1ccccc1 Show InChI InChI=1S/C17H12N2S/c1-13-19-17(12-20-13)8-7-14-9-16(11-18-10-14)15-5-3-2-4-6-15/h2-6,9-12H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against human recombinant mGlu5 receptor was determined by [Ca2+] flux assay using glutamate as agonist				Bioorg Med Chem Lett 14: 3993-6 (2004) Article DOI: 10.1016/j.bmcl.2004.05.037 BindingDB Entry DOI: 10.7270/Q2T43SKQ
					More data for this Ligand-Target Pair