Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50187630'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50187630 (CHEMBL208090 | N-(1-(3-methoxyphenyl)-3-phenyl-1H-...) Show SMILES COc1cccc(c1)-n1nc(cc1NC(=O)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H19N3O2/c1-28-20-14-8-13-19(15-20)26-22(24-23(27)18-11-6-3-7-12-18)16-21(25-26)17-9-4-2-5-10-17/h2-16H,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cells				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50187630 (CHEMBL208090 | N-(1-(3-methoxyphenyl)-3-phenyl-1H-...) Show SMILES COc1cccc(c1)-n1nc(cc1NC(=O)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H19N3O2/c1-28-20-14-8-13-19(15-20)26-22(24-23(27)18-11-6-3-7-12-18)16-21(25-26)17-9-4-2-5-10-17/h2-16H,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair