Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50187646'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50187646 (CHEMBL208157 | N-(cyclopentylmethyl)carboxyl-1,3-d...) Show SMILES O=C(CC1CCCC1)Nc1cc(nn1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H23N3O/c26-22(15-17-9-7-8-10-17)23-21-16-20(18-11-3-1-4-12-18)24-25(21)19-13-5-2-6-14-19/h1-6,11-14,16-17H,7-10,15H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cells				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50187646 (CHEMBL208157 | N-(cyclopentylmethyl)carboxyl-1,3-d...) Show SMILES O=C(CC1CCCC1)Nc1cc(nn1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H23N3O/c26-22(15-17-9-7-8-10-17)23-21-16-20(18-11-3-1-4-12-18)24-25(21)19-13-5-2-6-14-19/h1-6,11-14,16-17H,7-10,15H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair