Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50312134'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50312134 (3-chloro-N-(3-(cyclopropanecarboxamido)phenyl)benz...) Show SMILES Clc1cccc(c1)C(=O)Nc1cccc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C17H15ClN2O2/c18-13-4-1-3-12(9-13)17(22)20-15-6-2-5-14(10-15)19-16(21)11-7-8-11/h1-6,9-11H,7-8H2,(H,19,21)(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium flux				Bioorg Med Chem Lett 19: 6502-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.059 BindingDB Entry DOI: 10.7270/Q2JD4WZJ
					More data for this Ligand-Target Pair