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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50327683'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50327683
PNG
(2-(2-(Pyridin-2-yl)-6,7-dihydrooxazolo[4,5-c]pyrid...)
Show SMILES N#Cc1cccnc1N1CCc2oc(nc2C1)-c1ccccn1
Show InChI InChI=1S/C17H13N5O/c18-10-12-4-3-8-20-16(12)22-9-6-15-14(11-22)21-17(23-15)13-5-1-2-7-19-13/h1-5,7-8H,6,9,11H2
PDB
MMDB

KEGG

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PC cid
PC sid
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Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Sepracor Inc.

Curated by ChEMBL


Assay Description
Modulation of human recombinant mGluR5 expressed in CHO cells assessed as inhibition of glutamate-induced response

J Med Chem 53: 7107-18 (2010)


Article DOI: 10.1021/jm100736h
BindingDB Entry DOI: 10.7270/Q20G3KCJ
More data for this
Ligand-Target Pair