Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50382397'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50382397 (CHEMBL2022164) Show SMILES CN1CCC(=O)N=C1NC(=O)Nc1cccc(Br)c1 |c:6| Show InChI InChI=1S/C12H13BrN4O2/c1-17-6-5-10(18)15-11(17)16-12(19)14-9-4-2-3-8(13)7-9/h2-4,7H,5-6H2,1H3,(H2,14,15,16,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO-K1 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization				ACS Med Chem Lett 2: 882-884 (2011) Article DOI: 10.1021/ml200162f BindingDB Entry DOI: 10.7270/Q2XW4KT8
					More data for this Ligand-Target Pair