Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50392380 (CHEMBL2151622) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 22: 6469-74 (2012) Article DOI: 10.1016/j.bmcl.2012.08.044 BindingDB Entry DOI: 10.7270/Q23F4QR3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50392380 (CHEMBL2151622) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Lundbeck Research USA Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 22: 6469-74 (2012) Article DOI: 10.1016/j.bmcl.2012.08.044 BindingDB Entry DOI: 10.7270/Q23F4QR3 | |||||||||||
More data for this Ligand-Target Pair |