Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50392439'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50392439 (CHEMBL2151806) Show SMILES Fc1cccc(COc2ccc(cn2)C(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C19H21FN2O2/c20-16-6-4-5-14(11-16)13-24-18-10-9-15(12-21-18)19(23)22-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8,13H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization				Bioorg Med Chem Lett 22: 6481-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.043 BindingDB Entry DOI: 10.7270/Q2KD200S
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50392439 (CHEMBL2151806) Show SMILES Fc1cccc(COc2ccc(cn2)C(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C19H21FN2O2/c20-16-6-4-5-14(11-16)13-24-18-10-9-15(12-21-18)19(23)22-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8,13H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	28.8	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization				Bioorg Med Chem Lett 22: 6481-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.043 BindingDB Entry DOI: 10.7270/Q2KD200S
					More data for this Ligand-Target Pair