Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50411769'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50411769 (CHEMBL403390) Show SMILES Cc1cn2cc(cc2c(n1)C#Cc1ccsc1)C#N Show InChI InChI=1S/C15H9N3S/c1-11-8-18-9-13(7-16)6-15(18)14(17-11)3-2-12-4-5-19-10-12/h4-6,8-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR				Bioorg Med Chem Lett 18: 1804-9 (2008) Article DOI: 10.1016/j.bmcl.2008.02.024 BindingDB Entry DOI: 10.7270/Q27945W4
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