Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50420375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50420375 (CHEMBL2089191) Show SMILES NC(=O)c1cccc(c1)C#Cc1cccc(n1)C#N Show InChI InChI=1S/C15H9N3O/c16-10-14-6-2-5-13(18-14)8-7-11-3-1-4-12(9-11)15(17)19/h1-6,9H,(H2,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in Sprague-Dawley rat brain membrane after 60 mins by liquid scintillation counting				ACS Med Chem Lett 3: 544-549 (2012) Article DOI: 10.1021/ml3000726 BindingDB Entry DOI: 10.7270/Q21C1Z4G
					More data for this Ligand-Target Pair