Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50431723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50431723 (CHEMBL2346720) Show SMILES Cc1c(nn(C)c1-c1ccc(F)cc1)C(=O)Nc1ccnc(F)c1 Show InChI InChI=1S/C17H14F2N4O/c1-10-15(17(24)21-13-7-8-20-14(19)9-13)22-23(2)16(10)11-3-5-12(18)6-4-11/h3-9H,1-2H3,(H,20,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
SK Biopharmaceuticals Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 23: 2134-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.116 BindingDB Entry DOI: 10.7270/Q20R9QR5
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