Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50483145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Mus musculus)	BDBM50483145 (CHEMBL1630080) Show SMILES C[C@@H](OC(=O)Nc1cccc(F)c1)c1sc2nncn2c1C |r| Show InChI InChI=1S/C14H13FN4O2S/c1-8-12(22-13-18-16-7-19(8)13)9(2)21-14(20)17-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,17,20)/t9-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assay				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483145 (CHEMBL1630080) Show SMILES C[C@@H](OC(=O)Nc1cccc(F)c1)c1sc2nncn2c1C |r| Show InChI InChI=1S/C14H13FN4O2S/c1-8-12(22-13-18-16-7-19(8)13)9(2)21-14(20)17-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,17,20)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483145 (CHEMBL1630080) Show SMILES C[C@@H](OC(=O)Nc1cccc(F)c1)c1sc2nncn2c1C |r| Show InChI InChI=1S/C14H13FN4O2S/c1-8-12(22-13-18-16-7-19(8)13)9(2)21-14(20)17-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,17,20)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mGluR5				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair