Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50499233'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50499233 (CHEMBL3735107) Show SMILES CN1CCC(CC1)n1nnc2CC(CCc12)c1nc(no1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H23FN6O/c1-26-10-8-16(9-11-26)27-18-7-4-14(12-17(18)23-25-27)20-22-19(24-28-20)13-2-5-15(21)6-3-13/h2-3,5-6,14,16H,4,7-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a
Eisai Limited Curated by ChEMBL					Assay Description Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...				Bioorg Med Chem Lett 25: 5792-6 (2015) Article DOI: 10.1016/j.bmcl.2015.10.050 BindingDB Entry DOI: 10.7270/Q22B920X
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