Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM594149'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM594149 (6-[6-(3-chloro-5- | US11584732, Example 3) Show SMILES Fc1c(Cl)cc(cc1-c1cc(ncn1)-c1ccc(cn1)C#N)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description After thawing, membrane homogenates were re-suspended in the binding buffer (50 mM HEPES pH 7.5, 150 mM NaCl) to a final assay concentration of 2.5 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73JNN
					More data for this Ligand-Target Pair