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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 2' and Ligand = 'BDBM364245'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))		BDBM364245
PNG
(US9856257, 30)
Show SMILES CCNS(=O)(=O)c1ccc(cc1)-c1cc2n(CC(F)(F)F)c(=O)c3cn[nH]c3c2cn1
Show InChI InChI=1S/C19H16F3N5O3S/c1-2-25-31(29,30)12-5-3-11(4-6-12)15-7-16-13(8-23-15)17-14(9-24-26-17)18(28)27(16)10-19(20,21)22/h3-9,25H,2,10H2,1H3,(H,24,26)
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MMDB

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n/an/a 42n/an/an/an/an/an/a



Wyeth Research



Assay Description
For the enzymatic test, human MetAP2 protein was obtained from a culture supernatant of insect cells (sf9) infected with MetAP2 recombinant baculovir...

Bioorg Med Chem 15: 3321-33 (2007)


BindingDB Entry DOI: 10.7270/Q26T0PZK
More data for this
Ligand-Target Pair