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Found 1 hit Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 2' and Ligand = 'BDBM364277'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))		BDBM364277
PNG
(US9856257, 62)
Show SMILES CCCC(=O)Nc1ccccc1-c1cnc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1
Show InChI InChI=1S/C21H18F3N5O2/c1-2-5-17(30)27-15-7-4-3-6-13(15)12-8-16-19(25-9-12)18-14(10-26-28-18)20(31)29(16)11-21(22,23)24/h3-4,6-10H,2,5,11H2,1H3,(H,26,28)(H,27,30)
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n/an/a 46n/an/an/an/an/an/a



Wyeth Research



Assay Description
For the enzymatic test, human MetAP2 protein was obtained from a culture supernatant of insect cells (sf9) infected with MetAP2 recombinant baculovir...

Bioorg Med Chem 15: 3321-33 (2007)


BindingDB Entry DOI: 10.7270/Q26T0PZK
More data for this
Ligand-Target Pair