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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 2' and Ligand = 'BDBM50097412'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM50097412
PNG
(CHEMBL3586448 | US9856257, 37)
Show SMILES FC(F)(F)Cn1c2cc(cnc2c2[nH]ncc2c1=O)-c1cccnc1Cl
Show InChI InChI=1S/C16H9ClF3N5O/c17-14-9(2-1-3-21-14)8-4-11-13(22-5-8)12-10(6-23-24-12)15(26)25(11)7-16(18,19)20/h1-6H,7H2,(H,23,24)
PDB
MMDB

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Similars

US Patent
n/an/a 20n/an/an/an/an/an/a



Wyeth Research



Assay Description
For the enzymatic test, human MetAP2 protein was obtained from a culture supernatant of insect cells (sf9) infected with MetAP2 recombinant baculovir...


Bioorg Med Chem 15: 3321-33 (2007)


BindingDB Entry DOI: 10.7270/Q26T0PZK
More data for this
Ligand-Target Pair