Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Methionine--tRNA ligase, cytoplasmic' and Ligand = 'BDBM50129529'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50129529 (5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...) Show SMILES NC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1ccccn1 Show InChI InChI=1S/C21H14Cl2N4O/c22-15-8-9-16(17(23)11-15)13-4-6-14(7-5-13)19-12-18(21(24)28)26-27(19)20-3-1-2-10-25-20/h1-12H,(H2,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)				Bioorg Med Chem Lett 13: 2231-4 (2003) BindingDB Entry DOI: 10.7270/Q24Q7TCM
					More data for this Ligand-Target Pair
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50129529 (5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...) Show SMILES NC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1ccccn1 Show InChI InChI=1S/C21H14Cl2N4O/c22-15-8-9-16(17(23)11-15)13-4-6-14(7-5-13)19-12-18(21(24)28)26-27(19)20-3-1-2-10-25-20/h1-12H,(H2,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).				Bioorg Med Chem Lett 13: 2231-4 (2003) BindingDB Entry DOI: 10.7270/Q24Q7TCM
					More data for this Ligand-Target Pair