Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Methylcytosine dioxygenase TET2' and Ligand = 'BDBM50570895'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylcytosine dioxygenase TET2 (Homo sapiens)	BDBM50570895 (CHEMBL4859276) Show SMILES OC(=O)C(=C)CC(O)(C(O)=O)C(F)(F)F Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116141 BindingDB Entry DOI: 10.7270/Q2GB27V8
					More data for this Ligand-Target Pair
Methylcytosine dioxygenase TET2 (Homo sapiens)	BDBM50570895 (CHEMBL4859276) Show SMILES OC(=O)C(=C)CC(O)(C(O)=O)C(F)(F)F Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysis				Citation and Details Article DOI: 10.1016/j.bmc.2021.116141 BindingDB Entry DOI: 10.7270/Q2GB27V8
					More data for this Ligand-Target Pair