Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methylosome protein 50/Protein arginine N-methyltransferase 5' and Ligand = 'BDBM179393'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM179393 (US10307413, Compound 314 | US10391089, Compound 31...) Show SMILES CNCCNc1cc(ccn1)C(=O)NC[C@H](O)CN1CCc2ccccc2C1 |r| Show InChI InChI=1S/C21H29N5O2/c1-22-9-10-24-20-12-17(6-8-23-20)21(28)25-13-19(27)15-26-11-7-16-4-2-3-5-18(16)14-26/h2-6,8,12,19,22,27H,7,9-11,13-15H2,1H3,(H,23,24)(H,25,28)/t19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10391089 (2019) BindingDB Entry DOI: 10.7270/Q2RN3B7D
					More data for this Ligand-Target Pair