Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methylosome protein 50/Protein arginine N-methyltransferase 5' and Ligand = 'BDBM343952'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM343952 (US9777008, Compound 246) Show SMILES OC(CNc1cc(ccn1)-c1ncc2ccn(CC(=O)N3CCCCC3)c2n1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C30H35N7O2/c38-26(20-35-14-9-22-6-2-3-7-25(22)19-35)18-32-27-16-23(8-11-31-27)29-33-17-24-10-15-37(30(24)34-29)21-28(39)36-12-4-1-5-13-36/h2-3,6-8,10-11,15-17,26,38H,1,4-5,9,12-14,18-21H2,(H,31,32)	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9777008 (2017) BindingDB Entry DOI: 10.7270/Q26975QQ
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