Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microsomal triglyceride transfer protein large subunit' and Ligand = 'BDBM50184113'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein large subunit (Homo sapiens (Human))	BDBM50184113 (1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...) Show SMILES CCCN(CC)C(=O)[C@@H](NC(=O)c1ccc2N(CCc2c1)C(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C36H34F3N3O3/c1-3-21-41(4-2)35(45)32(25-10-6-5-7-11-25)40-33(43)27-16-19-31-26(23-27)20-22-42(31)34(44)30-13-9-8-12-29(30)24-14-17-28(18-15-24)36(37,38)39/h5-19,23,32H,3-4,20-22H2,1-2H3,(H,40,43)/t32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MTP in canine liver microsomes				Bioorg Med Chem Lett 16: 3039-42 (2006) Article DOI: 10.1016/j.bmcl.2006.02.058 BindingDB Entry DOI: 10.7270/Q2D21X68
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