Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microsomal triglyceride transfer protein large subunit' and Ligand = 'BDBM50184135'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein large subunit (Homo sapiens (Human))	BDBM50184135 (4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...) Show SMILES CCCNC(=O)[C@@H](NC(=O)CSc1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1 Show InChI InChI=1S/C33H30F3N3O3S/c1-2-20-37-32(42)30(23-8-4-3-5-9-23)39-29(40)21-43-26-18-16-25(17-19-26)38-31(41)28-11-7-6-10-27(28)22-12-14-24(15-13-22)33(34,35)36/h3-19,30H,2,20-21H2,1H3,(H,37,42)(H,38,41)(H,39,40)/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MTP in canine liver microsomes				Bioorg Med Chem Lett 16: 3039-42 (2006) Article DOI: 10.1016/j.bmcl.2006.02.058 BindingDB Entry DOI: 10.7270/Q2D21X68
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