Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM170543'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM170543 (US9085549, 59) Show SMILES Oc1ccc(cc1O)-c1cc(Br)c(s1)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H11BrO4S/c17-10-7-15(8-1-3-11(18)13(20)5-8)22-16(10)9-2-4-12(19)14(21)6-9/h1-7,18-21H	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
PROTEOTECH INC US Patent					Assay Description The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
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