Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM170548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM170548 (US9085549, 52) Show SMILES Oc1ccc(cc1O)C(=O)Nc1cc(O)c(O)cc1Br Show InChI InChI=1S/C13H10BrNO5/c14-7-4-11(18)12(19)5-8(7)15-13(20)6-1-2-9(16)10(17)3-6/h1-5,16-19H,(H,15,20)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
PROTEOTECH INC US Patent					Assay Description The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
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