Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM170574'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM170574 (US9085549, 98) Show SMILES CC(=O)N1N=C(CC1c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 |c:4| Show InChI InChI=1S/C17H16N2O5/c1-9(20)19-13(11-3-5-15(22)17(24)7-11)8-12(18-19)10-2-4-14(21)16(23)6-10/h2-7,13,21-24H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
PROTEOTECH INC US Patent					Assay Description The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
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