Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM170575'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM170575 (US9085549, 99) Show SMILES Oc1ccc(cc1O)-c1ccc(-c2ccc(O)c(O)c2)c(c1)N(=O)=O Show InChI InChI=1S/C18H13NO6/c20-15-5-2-11(8-17(15)22)10-1-4-13(14(7-10)19(24)25)12-3-6-16(21)18(23)9-12/h1-9,20-23H	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
PROTEOTECH INC US Patent					Assay Description The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
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