Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM50434484'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50434484 (CHEMBL2385165) Show SMILES CN(C)c1ccc(C=Cc2nc3ccc(I)cc3[nH]2)cc1 |w:8.8| Show InChI InChI=1S/C17H16IN3/c1-21(2)14-7-3-12(4-8-14)5-10-17-19-15-9-6-13(18)11-16(15)20-17/h3-11H,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...				Bioorg Med Chem 21: 3356-62 (2013) Article DOI: 10.1016/j.bmc.2013.02.054 BindingDB Entry DOI: 10.7270/Q23J3FB2
					More data for this Ligand-Target Pair