Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Ligand = 'BDBM121452'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM121452 (US8722709, 56) Show SMILES NC(=O)Nc1cc(ccn1)C1=C(CCCC1)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C18H18FN3O/c19-14-7-5-12(6-8-14)15-3-1-2-4-16(15)13-9-10-21-17(11-13)22-18(20)23/h5-11H,1-4H2,(H3,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...				US Patent US8722709 (2014) BindingDB Entry DOI: 10.7270/Q2NS0SJ4
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