Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM127621'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127621 (US8791118, 195) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(C[C@H](N)C(O)=O)cc1 |r| Show InChI InChI=1S/C28H30N6O3/c1-18(6-5-9-19-7-3-2-4-8-19)31-28(37)34-25-15-14-23-26(33-25)32-24(17-30-23)21-12-10-20(11-13-21)16-22(29)27(35)36/h2-4,7-8,10-15,17-18,22H,5-6,9,16,29H2,1H3,(H,35,36)(H2,31,32,33,34,37)/t18-,22+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair