Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM275313'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM275313 (1-[(1S)-2-hydroxy-2-methyl-1- phenylpropyl]-3[-1-(...) Show SMILES Cn1cc2cc(ccc2n1)-n1ncc2cc(NC(=O)N[C@@H](c3ccccc3)C(C)(C)O)ncc12 |r| Show InChI InChI=1S/C25H25N7O2/c1-25(2,34)23(16-7-5-4-6-8-16)29-24(33)28-22-12-17-13-27-32(21(17)14-26-22)19-9-10-20-18(11-19)15-31(3)30-20/h4-15,23,34H,1-3H3,(H2,26,28,29,33)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...				US Patent US9884048 (2018) BindingDB Entry DOI: 10.7270/Q29G5PT5
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