Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM275392'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM275392 (1-[1-(2,6- difluorobenzyl)pyrrolidin-3- yl]-3-[1-(...) Show SMILES Cc1cc(ccn1)-n1ncc2cc(NC(=O)NC3CCN(Cc4c(F)cccc4F)C3)ncc12 Show InChI InChI=1S/C24H23F2N7O/c1-15-9-18(5-7-27-15)33-22-12-28-23(10-16(22)11-29-33)31-24(34)30-17-6-8-32(13-17)14-19-20(25)3-2-4-21(19)26/h2-5,7,9-12,17H,6,8,13-14H2,1H3,(H2,28,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...				US Patent US9884048 (2018) BindingDB Entry DOI: 10.7270/Q29G5PT5
					More data for this Ligand-Target Pair