Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM383280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM383280 (4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...) Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r| Show InChI InChI=1S/C24H20ClN7O/c1-31-21(7-9-27-31)28-20-11-16(6-8-26-20)17-12-22-29-30-24-18(14-33-23(13-17)32(22)24)10-15-2-4-19(25)5-3-15/h2-9,11-13,18H,10,14H2,1H3,(H,26,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University					Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...				J Med Chem 51: 5009-18 (2008) BindingDB Entry DOI: 10.7270/Q23X88ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM383280 (4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...) Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r| Show InChI InChI=1S/C24H20ClN7O/c1-31-21(7-9-27-31)28-20-11-16(6-8-26-20)17-12-22-29-30-24-18(14-33-23(13-17)32(22)24)10-15-2-4-19(25)5-3-15/h2-9,11-13,18H,10,14H2,1H3,(H,26,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University					Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...				J Med Chem 51: 5009-18 (2008) BindingDB Entry DOI: 10.7270/Q23X88ZR
					More data for this Ligand-Target Pair