Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM383337'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM383337 (4-(9-((5-chloropyridin-3- yl)oxy)-8,9-dihydro-7H-6...) Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OCC[C@H](Oc3cncc(Cl)c3)c3nnc(c1)n23 |r| Show InChI InChI=1S/C23H19ClN8O2/c1-31-20(3-6-27-31)28-19-8-14(2-5-26-19)15-9-21-29-30-23-18(4-7-33-22(10-15)32(21)23)34-17-11-16(24)12-25-13-17/h2-3,5-6,8-13,18H,4,7H2,1H3,(H,26,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University					Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...				J Med Chem 51: 5009-18 (2008) BindingDB Entry DOI: 10.7270/Q23X88ZR
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