Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM418273'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM418273 ((2R)-2-(6-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...) Show SMILES C[C@@H](N1Cc2ccc(cc2C1=O)-c1nc(Nc2cnn(C)n2)ncc1Cl)C(=O)N[C@H](CO)c1nc(ccc1F)N(C)C |r| Show InChI InChI=1S/C27H28ClFN10O3/c1-14(25(41)32-20(13-40)24-19(29)7-8-22(34-24)37(2)3)39-12-16-6-5-15(9-17(16)26(39)42)23-18(28)10-30-27(35-23)33-21-11-31-38(4)36-21/h5-11,14,20,40H,12-13H2,1-4H3,(H,32,41)(H,30,33,35,36)/t14-,20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...				US Patent US11001575 (2021) BindingDB Entry DOI: 10.7270/Q2TB1B01
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM418273 ((2R)-2-(6-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...) Show SMILES C[C@@H](N1Cc2ccc(cc2C1=O)-c1nc(Nc2cnn(C)n2)ncc1Cl)C(=O)N[C@H](CO)c1nc(ccc1F)N(C)C |r| Show InChI InChI=1S/C27H28ClFN10O3/c1-14(25(41)32-20(13-40)24-19(29)7-8-22(34-24)37(2)3)39-12-16-6-5-15(9-17(16)26(39)42)23-18(28)10-30-27(35-23)33-21-11-31-38(4)36-21/h5-11,14,20,40H,12-13H2,1-4H3,(H,32,41)(H,30,33,35,36)/t14-,20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...				US Patent US10457669 (2019) BindingDB Entry DOI: 10.7270/Q2B27XNR
					More data for this Ligand-Target Pair