Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM495246'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM495246 (1-(2,3-Difluorobenzyl)-4-(5-morpholino-1H-pyrrolo[...) Show SMILES Fc1cccc(Cn2ccc(cc2=O)-c2c[nH]c3ncc(cc23)N2CCOCC2)c1F Show InChI InChI=1S/C23H20F2N4O2/c24-20-3-1-2-16(22(20)25)14-29-5-4-15(10-21(29)30)19-13-27-23-18(19)11-17(12-26-23)28-6-8-31-9-7-28/h1-5,10-13H,6-9,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2DZ0DDB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM495246 (1-(2,3-Difluorobenzyl)-4-(5-morpholino-1H-pyrrolo[...) Show SMILES Fc1cccc(Cn2ccc(cc2=O)-c2c[nH]c3ncc(cc23)N2CCOCC2)c1F Show InChI InChI=1S/C23H20F2N4O2/c24-20-3-1-2-16(22(20)25)14-29-5-4-15(10-21(29)30)19-13-27-23-18(19)11-17(12-26-23)28-6-8-31-9-7-28/h1-5,10-13H,6-9,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<150	n/a	n/a	n/a	n/a	n/a	n/a
AGV DISCOVERY; INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); UNIVERSITE DE MONTPELLIER US Patent					Assay Description To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...				US Patent US10995089 (2021) BindingDB Entry DOI: 10.7270/Q2W95D9P
					More data for this Ligand-Target Pair