Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1 [8-360]' and Ligand = 'BDBM192415'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human))	BDBM192415 (US9187462, II-25) Show SMILES Cn1cc(cn1)[C@@H](NC(=O)c1ccc2cnc(Nc3ccnn3C)nc2c1)c1ccc(Cl)c(F)c1 |r| Show InChI InChI=1S/C24H20ClFN8O/c1-33-13-17(12-29-33)22(14-5-6-18(25)19(26)9-14)32-23(35)15-3-4-16-11-27-24(30-20(16)10-15)31-21-7-8-28-34(21)2/h3-13,22H,1-2H3,(H,32,35)(H,27,30,31)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.3	n/a
Array BioPharma Inc.; Genentech, Inc. US Patent					Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...				US Patent US9187462 (2015) BindingDB Entry DOI: 10.7270/Q21G0K2P
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