Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM24717'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM24717 (3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{10,15}]he...) Show SMILES OCc1[nH]nc-2c1CCc1c-2[nH]c2ccccc12 Show InChI InChI=1S/C14H13N3O/c18-7-12-10-6-5-9-8-3-1-2-4-11(8)15-13(9)14(10)17-16-12/h1-4,15,18H,5-7H2,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair