Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50492944'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492944 (CHEMBL2414925) Show SMILES COc1cc(OC)c2c3CCc4c[nH]nc4-c3[nH]c2c1 Show InChI InChI=1S/C15H15N3O2/c1-19-9-5-11-13(12(6-9)20-2)10-4-3-8-7-16-18-14(8)15(10)17-11/h5-7,17H,3-4H2,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair