Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10' and Ligand = 'BDBM392717'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM392717 (Example 11 | US10301291, Compound 11e) Show SMILES Clc1ccc(cc1Cl)-c1ncc(CC#N)n1-c1ccnc(NC2CCCCC2)n1 Show InChI InChI=1S/C21H20Cl2N6/c22-17-7-6-14(12-18(17)23)20-26-13-16(8-10-24)29(20)19-9-11-25-21(28-19)27-15-4-2-1-3-5-15/h6-7,9,11-13,15H,1-5,8H2,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description First of all, after a substrate was inserted into a prepared base reaction buffer solution (20 mM Hepes (pH 75), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35...				J Med Chem 52: 1994-2005 (2009) BindingDB Entry DOI: 10.7270/Q20K2BW1
					More data for this Ligand-Target Pair