Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50122913'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50122913 (6-[2-(2,4-Difluoro-phenyl)-imidazo[1,2-a]pyridin-3...) Show SMILES Cc1ccccc1-n1nc(ccc1=O)-c1c(nc2ccccn12)-c1ccc(F)cc1F Show InChI InChI=1S/C24H16F2N4O/c1-15-6-2-3-7-20(15)30-22(31)12-11-19(28-30)24-23(17-10-9-16(25)14-18(17)26)27-21-8-4-5-13-29(21)24/h2-14H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Tumor necrosis factor alpha release from LPS-induced THP-1 cells by ELISA				J Med Chem 46: 349-52 (2003) Article DOI: 10.1021/jm025585h BindingDB Entry DOI: 10.7270/Q27P8XRR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50122913 (6-[2-(2,4-Difluoro-phenyl)-imidazo[1,2-a]pyridin-3...) Show SMILES Cc1ccccc1-n1nc(ccc1=O)-c1c(nc2ccccn12)-c1ccc(F)cc1F Show InChI InChI=1S/C24H16F2N4O/c1-15-6-2-3-7-20(15)30-22(31)12-11-19(28-30)24-23(17-10-9-16(25)14-18(17)26)27-21-8-4-5-13-29(21)24/h2-14H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of LPS-induced p38-related Tumor necrosis factor alpha release in human whole blood				J Med Chem 46: 349-52 (2003) Article DOI: 10.1021/jm025585h BindingDB Entry DOI: 10.7270/Q27P8XRR
					More data for this Ligand-Target Pair