Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM142614'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM142614 (US8933228, 30) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)c3ccccc23)n(n1)-c1ccc(C)cc1 Show InChI InChI=1S/C31H27N7O3/c1-18(2)24-16-27(38(37-24)20-10-8-19(3)9-11-20)35-31(40)34-23-12-13-25(22-7-5-4-6-21(22)23)41-26-14-15-32-30-29(26)33-17-28(39)36-30/h4-18H,1-3H3,(H,32,36,39)(H2,34,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...				US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW
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