BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM342102'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 12


(Homo sapiens (Human))		BDBM342102
PNG
(1-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-3-(4-(...)
Show SMILES COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)n2)cc(OC)c1
Show InChI InChI=1S/C37H45N7O7/c1-37(2,3)32-24-33(44(4)43-32)41-36(45)40-30-11-12-31(29-10-8-7-9-28(29)30)51-34-13-14-38-35(42-34)39-25-21-26(47-6)23-27(22-25)50-20-19-49-18-17-48-16-15-46-5/h7-14,21-24H,15-20H2,1-6H3,(H,38,39,42)(H2,40,41,45)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED

US Patent


Assay Description
p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...

US Patent US9771353 (2017)


BindingDB Entry DOI: 10.7270/Q2HQ4219
More data for this
Ligand-Target Pair