Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM125210'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM125210 (US8772481, 10) Show SMILES Fc1ccc(Nc2ccc3c(nncc3n2)-c2ccc(F)cc2F)c(F)c1 Show InChI InChI=1S/C19H10F4N4/c20-10-1-3-12(14(22)7-10)19-13-4-6-18(26-17(13)9-24-27-19)25-16-5-2-11(21)8-15(16)23/h1-9H,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.5	n/a
Amgen Inc. US Patent					Assay Description Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...				US Patent US8772481 (2014) BindingDB Entry DOI: 10.7270/Q2ZP44T4
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