Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14836 (3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 21 | n/a | n/a | n/a | 7.0 | 23 |
Boehringer Ingelheim Pharmaceuticals Inc. | Assay Description The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re... | J Med Chem 46: 4669-75 (2003) Article DOI: 10.1021/jm030120s BindingDB Entry DOI: 10.7270/Q2833Q8J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14836 (3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | n/a | 0.00160 | 7.33E+4 | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for Mitogen-activated protein kinase p38 alpha | Bioorg Med Chem Lett 13: 3101-4 (2003) BindingDB Entry DOI: 10.7270/Q2CR5SSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14836 (3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 7.33E+4 | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Rate of association to Mitogen-activated protein kinase p38 alpha | Bioorg Med Chem Lett 13: 3101-4 (2003) BindingDB Entry DOI: 10.7270/Q2CR5SSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14836 (3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for Mitogen-activated protein kinase p38 alpha | Bioorg Med Chem Lett 13: 3101-4 (2003) BindingDB Entry DOI: 10.7270/Q2CR5SSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |