Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM15430'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15430 (1,3-dimethyl-5-[2-(thiophen-2-yl)-4-[3-(trifluorom...) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-c1nc([nH]c1-c1cccc(c1)C(F)(F)F)-c1cccs1 Show InChI InChI=1S/C23H17F3N4OS/c1-29-16-9-8-14(12-17(16)30(2)22(29)31)20-19(27-21(28-20)18-7-4-10-32-18)13-5-3-6-15(11-13)23(24,25)26/h3-12H,1-2H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.2	30
Pfizer					Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...				Bioorg Med Chem Lett 14: 919-23 (2004) Article DOI: 10.1016/j.bmcl.2003.12.023 BindingDB Entry DOI: 10.7270/Q28050V6
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