Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM15440'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15440 (5-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-c1nc([nH]c1-c1ccc(F)cc1)-c1ccc(cc1)S(C)=O Show InChI InChI=1S/C25H21FN4O2S/c1-29-20-13-8-17(14-21(20)30(2)25(29)31)23-22(15-4-9-18(26)10-5-15)27-24(28-23)16-6-11-19(12-7-16)33(3)32/h4-14H,1-3H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...				Bioorg Med Chem Lett 14: 919-23 (2004) Article DOI: 10.1016/j.bmcl.2003.12.023 BindingDB Entry DOI: 10.7270/Q28050V6
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