Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM16352'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM16352 (5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6...) Show SMILES CC(C)c1nnc2ccc(cn12)-c1ocnc1-c1c(F)cc(F)cc1F |(-5.34,-5.49,;-4.57,-4.15,;-3.03,-4.15,;-5.34,-2.82,;-6.87,-2.98,;-7.5,-1.57,;-6.35,-.54,;-6.35,1,;-5.02,1.77,;-3.69,1,;-3.69,-.54,;-5.02,-1.31,;-2.52,2,;-1.02,1.64,;-.22,2.96,;-1.22,4.13,;-2.64,3.53,;-3.97,4.3,;-3.97,5.85,;-2.64,6.62,;-5.31,6.62,;-6.64,5.85,;-7.98,6.62,;-6.64,4.3,;-5.31,3.53,;-5.31,1.99,)| Show InChI InChI=1S/C18H13F3N4O/c1-9(2)18-24-23-14-4-3-10(7-25(14)18)17-16(22-8-26-17)15-12(20)5-11(19)6-13(15)21/h3-9H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...				Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ
					More data for this Ligand-Target Pair