Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM19432'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM19432 (4-[3-(4-chlorophenyl)-5-(4-methylpiperidin-1-yl)-1...) Show SMILES CC1CCN(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN4/c1-14-8-12-25(13-9-14)20-18(15-6-10-22-11-7-15)19(23-24-20)16-2-4-17(21)5-3-16/h2-7,10-11,14H,8-9,12-13H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.5	30
Pfizer					Assay Description Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...				J Med Chem 50: 5712-9 (2007) Article DOI: 10.1021/jm0611915 BindingDB Entry DOI: 10.7270/Q20G3HD5
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